Coronavirus

COVID-19 – Why Aren’t We Bolstering Immune Defense with Nutrition?

Leave a Comment / Resilient! The Redox Health Newsletter / Michael Sherer

The public health community understood the gravity of COVID-19 as a threat long before the political leaders and the general populace did for one simple reason: they knew we weren’t prepared for a virus with this combination of lethality and the ability to spread before you knew you had it. We didn’t have testing capacity […]

COVID-19 – Why Aren’t We Bolstering Immune Defense with Nutrition? Read More »

3-Month Melatonin Supplementation to Reduce Brain Oxidative Stress and Improve Sleep in Mild Cognitive Impairment: A Randomised Controlled Feasibility Trial December 20, 2024
Melatonin has multiple proposed therapeutic benefits including antioxidant properties, circadian rhythm synchronisation and sleep promotion. Since these areas are also recognised risk factors for dementia, melatonin has been hypothesised to slow cognitive decline in older adults. Participants with Mild Cognitive Impairment (MCI) were recruited from the community for a 12-week randomised placebo-controlled parallel, feasibility trial […]
Tubastrine, an antioxidant molecule from Tubastraea tagusensis sun coral, in the reversion of oxidative stress and neuron's death induced by Abeta42 December 20, 2024
Alzheimer's disease (AD) is a progressive neurodegenerative disorder involving mitochondrial dysfunction and consequent production of reactive oxygen species (ROS), generated after amyloid peptide (Aβ42) accumulation. In this study, we isolated a new antioxidant molecule from the sun coral Tubastraea tagusensis and analysed it in cells exposed to oligomeric amyloid-beta peptide 1-42 (oAβ42). The coral was […]
Protective effects of quercetin against tongue injury and oxidative stress triggered by irinotecan: a histopathological, biochemical and molecular study December 20, 2024
CONCLUSION: QRT possess protective properties against CPT-11-triggered tongue injury.
Molecular disruptions in microalgae caused by Acidithiobacillus ferrooxidans: Photosynthesis, oxidative stress, and energy metabolism in acid mine drainage December 20, 2024
Microalgae are recognized for their potential in the bioremediation of acid mine drainage (AMD), despite the challenges posed by AMD's low pH, high heavy metal content, and oligotrophic conditions. However, the impact of AMD chemoautotrophic microorganisms on microalgal growth and remediation efforts within AMD has been largely overlooked. This study aims to elucidate the effects […]
Prx5 overexpression protect against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress and inflammation via the TLR4/NF-kappaB pathway December 20, 2024
CONCLUSION: Prx5 overexpression could protect against DOX-induced cardiac oxidative stress and inflammation. Mechanistically, Prx5 overexpression potentially inhibits the TLR4/NF-κB signaling pathway to improve DOX-induced myocardial injury. These findings strongly suggest that Prx5 could be a potential candidate target for the treatment of DOX-induced myocardial injury.