January 2024

Grapefruit Mock-tail

Leave a Comment / Resilient Eating / Melinda Sherer

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Honey Mint Lemonade

Leave a Comment / Resilient Eating / Melinda Sherer

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Metabolic and Oxidative Stress Responses in Nile Tilapia (Oreochromis niloticus) During Cadmium Exposure and Recovery July 10, 2026
Heavy metal contamination of freshwater ecosystems poses a global threat to biodiversity and food security. Cadmium, a highly toxic and persistent nonessential metal, accumulates in aquatic organisms and disrupts physiological functions and ecosystem stability. This study evaluates the chronic effects of cadmium exposure on Nile tilapia (Oreochromis niloticus) to identify integrated biomarkers for environmental monitoring. […]
Development of a Biology-Informed Chemical Mixture Index for Oxidative Stress and Mortality in NHANES 2005-2010: A Survey-Weighted Quantile G-Computation Approach July 10, 2026
BACKGROUND: Current chemical mixture approaches are largely data-driven without considering shared biological mechanisms among mixture components, highlighting the need for biology-informed approaches.
Age-Dependent Spatiotemporal Remodeling of Brain Sphingolipids During LPS-Induced Neuroinflammation: MALDI-MSI Reveals Accelerated Sphingomyelin Depletion and Sulfatide Accumulation Linked to Mitochondrial Oxidative Stress July 10, 2026
Aging is a major risk factor for exacerbated neuroinflammation and neurodegenerative diseases, yet the underlying lipid metabolic mechanisms remain incompletely understood. Here, we employed high-resolution matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) combined with quantitative peak-area analysis and conceptual kinetic modeling to investigate age-dependent sphingolipid remodeling in the rat brain following intracerebro-ventricular (ICV) LPS challenge. […]
Taurine attenuates polystyrene microplastic-associated oxidative stress, inflammation, and apoptotic changes in the spleen of mice July 10, 2026
CONCLUSION: These findings demonstrated that TN exerts protective effects against PMPs-induced oxidative stress, inflammation, apoptosis, and immune-related alterations in splenic tissue. TN partially attenuated PMPs-induced immunotoxic and histopathological changes in this experimental mouse model, although further mechanistic, dose-response, and functional immune studies are required to confirm its potential therapeutic or nutraceutical applications against PMPs -induced […]
Natural defense against colorectal cancer: the effects of kaempferol on epigenetics, apoptosis, inflammation, oxidative stress, and cell proliferation July 10, 2026
Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide, driven by complex genetic, epigenetic, and environmental factors. Among natural bioactive compounds, kaempferol (a dietary flavonoid found abundantly in fruits, vegetables, and medicinal plants) has garnered significant attention for its promising anticancer properties. Accumulating evidence suggests that kaempferol exerts multifaceted effects on […]