Melinda Sherer

Chicken Skewers

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Chicken & Veggie Quinoa Bowl

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Oxidative stress, serum metabolites, inflammatory cytokine changes associated with lumpy skin disease in cattle December 9, 2025
CONCLUSIONS: Understanding the underlying mechanisms of LSD infection can help in devising suitable anti-oxidant and immunomodulatory interventions and strategies to mitigate tissue damage, bolster the host immune response, and effectively manage LSD outbreaks in cattle.
Qishen Yiqi Dripping Pills Activate HDAC3-Mediated Nrf2-PITX2 Signaling Pathway to Reduce Oxidative Stress and Alleviate Myocardial Infarction Injury in Mice December 9, 2025
CONCLUSIONS: QSYQ effectively ameliorates MI injury, at least in part, by inhibiting HDAC3, which consequently activates the Nrf2/PITX2 signaling pathway and suppresses oxidative stress damage. Mechanistically, cryptotanshinone is identified as the critical molecular entity directly targeting HDAC3 to mediate this cardioprotective effect.
Ruminal microbial dysbiosis induces mastitis in dairy goats by activating oxidative stress and ferritinophagy-ferroptosis December 9, 2025
Recent studies indicate that ruminal microbiota dysbiosis plays a significant role in the development of mastitis in ruminants, though the exact mechanisms remain incompletely understood. In this study, a high-concentration (HC) diet led to subacute ruminal acidosis (SARA) in dairy goats, as evidenced by prolonged daily periods of ruminal pH below 5.8. The HC group […]
Da-Bu-Yin-Wan and Qian-Zheng-San Alleviate Parkinson's Disease by Activating the Keap1/Nrf2/HO-1 Pathway to Positively Regulate Oxidative Stress December 9, 2025
CONCLUSION: This study elucidated that BYQZF improved PD through the Keap1/Nrf2/HO-1 signaling pathway and alleviated oxidative stress, which is beneficial for inspiring new strategies for drug development targeting PD.
FoxO1 Responses to Chronic Oxidative Stress to Participate in Age-Related Osteoporosis by Depriving beta-Catenin From TCF7 December 9, 2025
The increasing prevalence of age-related osteoporosis has emerged as a critical public health issue in the context of the globally aging population. Chronic oxidative stress, induced by excessive reactive oxygen species (ROS) associated with aging, is a critical factor underlying the development of osteoporosis in elderly individuals and a diminished capacity for bone formation and […]