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Association of Oxidative Stress With Biochemical Markers in Diabetic and Non-diabetic Chronic Kidney Disease Patients: A Cross-Sectional Study March 9, 2026
Background Chronic kidney disease (CKD) is exacerbated by oxidative stress (OS), which accelerates renal injury and cardiovascular complications. Diabetes intensifies OS via hyperglycemia and mitochondrial dysfunction, promoting faster decline in diabetic kidney disease (DKD). This study compares OS markers with standard biochemical parameters in diabetic versus non-diabetic CKD to inform risk stratification and management. Methods […]
Dose-optimized HILT promotes peripheral nerve repair through BMP4-Smad9-mediated inhibition of neuroinflammation and oxidative stress March 9, 2026
Evidence has shown that high-intensity laser therapy (HILT) may be beneficial for recovery after peripheral nerve injury (PNI). However, the optimized doses and effective mechanisms remain unclear. The present study sought to explore the effects of various doses of HILT on the recovery of nerve function in sciatic nerve injury (SNI) rats. The potential mechanism […]
Tianhuang formula attenuates cardiomyocyte pyroptosis in myocardial infarction by suppressing oxidative stress and the cGAS-STING-NLRP3 axis March 9, 2026
CONCLUSIONS: THF exerts cardioprotective effects by reducing oxidative stress, modulating the cGAS-STING-NLRP3 axis, and inhibiting cardiomyocyte pyroptosis, supporting its traditional use and highlighting its potential as a therapeutic candidate for MI.
Visnagin Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Reducing Ferroptosis March 9, 2026
CONCLUSIONS: Visnagin exerts protective actions through both modulation of Akt/Nrf2 signaling ACSL4/TfR1 signaling and direct free radical scavenging. These findings underscore visnagin's potential as a multitarget therapeutic agent for SA-AKI.
Oxidative stress in adolescents with overweight/obesity March 9, 2026
CONCLUSIONS: The present study provides evidence of disrupted redox homeostasis in adolescents with obesity. Obesity is tightly connected with increased oxidative stress and a cluster of metabolic abnormalities. It is essential to identify risk factors promptly and develop a strategy to combat obesity and its associated diseases.